To Detach, Migrate, Adhere, and Metastasize: CD97/ADGRE5 in Cancer
Tumorigenesis is a multistep process, during which cells acquire a series of mutations that lead to unrestrained cell growth and proliferation, inhibition of cell differentiation, and evasion of cell death.Growing tumors stimulate Bottle Teat angiogenesis, providing them with nutrients and oxygen.Ultimately, tumor cells invade the surrounding tissu